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A Congressional investigation revealed that Pfizer agreed to pay Dr. Jarvik $1,350,000 as a celebrity pitchman for the heart drug Lipitor, and wants to know how much stunt doubles in the ads may have also been paid.

Celebrity advertising endorsements are nothing new, of course. But the Lipitor campaign is a rare instance of a well-known doctor's endorsing a drug in advertising - and it has helped rekindle a smoldering debate over whether it is appropriate to aim ads for prescription drugs directly at consumers.

With minimal public notice and no formal environmental review, the Forest Service has approved a permit allowing a British mining company to explore for uranium just outside Grand Canyon National Park, less than three miles from a popular lookout over the canyon's southern rim.

Peasant farmers from the northern Salvadoran province of Cabañas fear that mining operations planned for the region will consume 30,000 litres of water a day, drawn from the same sources that currently provide local residents with water only once a week.

The CEOs of three-quarters of the world's 100 largest companies have just completed an uncomfortable weekend at the tiny Swiss ski resort of Davos, while their companies' share prices nosedived on global stock markets, amid concern that the U.S. economy is staggering towards recession.

A decision by India's highest court may force international companies who outsource business here to do more to guard the safety of local workers.

Oxy is Occidental Petroleum, the California-based company that pulled a fortune from this rain forest from 1972 to 2000. It is also the company that Maynas and other Achuar leaders now blame for wreaking environmental havoc -- and leaving many of the people here ill.

Altria Group Inc. said Wednesday it would spin off its international tobacco business on March 28, freeing it to pursue cigarette sales more aggressively without ties to its U.S. counterpart - and U.S. regulatory oversight.

A huge state-owned Chinese pharmaceutical company that exports to dozens of countries, including the United States, is at the center of a nationwide drug scandal after nearly 200 Chinese cancer patients were paralyzed or otherwise harmed last summer by contaminated leukemia drugs.

Unlike more established competitors, Mr. Giustra was a newcomer to uranium mining in Kazakhstan, a former Soviet republic. But what his fledgling company lacked in experience, it made up for in connections. Accompanying Mr. Giustra on his luxuriously appointed MD-87 jet that day was a former president of the United States, Bill Clinton.